What causes acinar cell damage?
Activated en- zymes are directly damaging to the acinar cell themselves, but recruitment of circulat- ing neutrophils leads to further cellular damage. Cytokines and neutrophil activation are also responsible for the systemic inflammatory response typically seen in severe acute pancreatitis.
Activated en- zymes are directly damaging to the acinar cell themselves, but recruitment of circulat- ing neutrophils leads to further cellular damage. Cytokines and neutrophil activation are also responsible for the systemic inflammatory response typically seen in severe acute pancreatitis.
