Is actin positive or negative?
Actin exists in a state of constant remodeling, where filaments grow at the positive end and depolymerize at the minus end. ATP-bound G-actin can be incorporated into the growing actin filament. Actin has intrinsic ATPase activity, which cleaves the ATP to ADP, thus favoring disassembly into G-actin monomers (Fig. 4A).
Actin exists in a state of constant remodeling, where filaments grow at the positive end and depolymerize at the minus end. ATP-bound G-actin can be incorporated into the growing actin filament. Actin has intrinsic ATPase activity, which cleaves the ATP to ADP, thus favoring disassembly into G-actin monomers (Fig. 4A).
