Is acetylation positive or negative?
Acetylation adds a negative charge to positively charged lysines, reducing the strong interaction between DNA and the histone octamer or nucleosome–nucleosome interactions resulting in an open chromatin architecture [2,16,32].
Acetylation adds a negative charge to positively charged lysines, reducing the strong interaction between DNA and the histone octamer or nucleosome–nucleosome interactions resulting in an open chromatin architecture [2,16,32].
