How is acetoacetate removed from the body?
Nonenzymatic decarboxylation of acetoacetate yields acetone, which is eliminated via the lungs. The pathways of formation of ketone bodies are shown in Figure 18-9. The major pathway of production of acetoacetate is from β-hydroxy-β-methylglutaryl-CoA (HMG-CoA).
Nonenzymatic decarboxylation of acetoacetate yields acetone, which is eliminated via the lungs. The pathways of formation of ketone bodies are shown in Figure 18-9. The major pathway of production of acetoacetate is from β-hydroxy-β-methylglutaryl-CoA (HMG-CoA).
